Century-starting year (3 letters)

{ Answer }

MDI

{ Related Clues }

Year Vespucci sailed to the New World
Late Middle Ages date
Year that Michelangelo began work on "David"
Year in Pope Alexander VI's reign
When Luther was 18
16th-century start
Year in Ivan the Great's rule
Year in Luther's time
Year that Michelangelo sculpted the "Pietà"
Year in Henry VII's reign
Year in a voyage by Amerigo Vespucci
Roman 1501
1501, on a monument
Nero's 1501
16th-century opener
Year of an Amerigo Vespucci voyage
16th-century date
Year Michelangelo began "David"
Start of the 16th century
Year Michelangelo began work on "David"
Year in an Amerigo Vespucci voyage

{ Tags }

16th, amerigo, began, century, date, david, henry, luthers, mdi, michelangelo, reign, roman, start, starting, time, vespucci, viis, voyage, work, year, 1501

{ Notes }

The answer MDI is uncommon, appearing about once every 450 puzzles.

{ Definition }

MDI as a noun:

1. (Markaz-ud-Dawa-wal-Irshad, MDI) = a Sunni organization formed in 1989 and based in Pakistan; opposes missionary groups from the United States; has Lashkar-e-Tayyiba as its armed wing